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Apr 5, 2008

California DUI Lawyer Center Blog: False-positive breath-alcohol test after a ketogenic diet

Interesting. With the push for low calorie diets and the idea that this action will prolong life, you may want to watch out for the cops if you try this diet out! Seems that the diet can lead to a DWI offense or a failed work required physical..


False-positive breath-alcohol test after a ketogenic diet
California drunk driving criminal defense attorney article

False-positive breath-alcohol test after a ketogenic diet

A 59-year-old man undergoing weight loss with very low calorie diets (VLCD) attempted to drive a car, which was fitted with an alcohol ignition interlock device, but the vehicle failed to start. Because the man was a teetotaler, he was surprised and upset by this result.

VLCD treatment leads to ketonemia with high concentrations of acetone, acetoacetate and b-hydroxybutyrate in the blood. The interlock device determines alcohol (ethanol) in breath by electrochemical oxidation, but acetone does not undergo oxidation with this detector. However, under certain circumstances acetone is reduced in the body to isopropanol by hepatic alcohol dehydrogenase (ADH). The ignition interlock device responds to other alcohols (e.g. methanol, n-propanol and isopropanol), which therefore explains the false-positive result. This ‘side effect’ of ketogenic diets needs further discussion by authorities when people engaged in safety-sensitive work (e.g. bus drivers and airline pilots) submit to random breath-alcohol
tests.

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